Bush is a native of Tiburon, California. She has made guest appearances on television series such as CSI: Miami, Moonlight and Ghost Whisperer. In 2007, she co-starred alongside Tom Arnold in Palo Alto and then appeared in the 2008 film Fling. She made her theatrical debut in her best-known role to date as Megan White in Dance Flick which was released on May 22, 2009. The film grossed $28,728,151 worldwide. The same year, Bush had a small role in the film Fired Up.