Vickers was married three times; to A. C. Lyles (March 15, 1948 – September 28, 1948), Mickey Rooney (June 3, 1949 – September 25, 1951) and actor Manuel Rojas (September 1, 1954 – May 5, 1965). Each marriage ended in divorce. Vickers had one son with Mickey Rooney, and two daughters with Rojas.