A native of the Bronx, Weinrib got his start in show Business working with Spike Jones, then later in The Billy Barnes Revue. He made guest appearances on The Dick Van Dyke Show, The Many Loves of Dobie Gillis, Burke's Law, The Munsters, Happy Days and Adam-12. He charted nationally (Music Vendor, #132) with the comedy single "Prez Conference" in 1962. He also guest starred in an Emergency! episode called "Firehouse Four" as Fred Gibson, an overweight, accident-prone man. Woody Allen's character in his 1995 film Mighty Aphrodite was named "Lenny Weinrib."