Alongside theatre work, including a role in 2013's Macbeth starring James McAvoy at Trafalgar Studios, Guthrie had a starring role in 2013's musical drama Sunshine on Leith. He appeared in the pilots of the British sitcoms Two Doors Down (2013) and Miller's Mountain (2014), although did not participate in the shows, which were negatively reviewed. In 2015 he acted in Robert Carlyle's poorly received directorial debut The Legend of Barney Thomson and in the role of Ewan Tavendale in Terence Davies's adaptation of the novel Sunset Song, opposite Agyness Deyn.