Klausner is head Writer and co-executive Producer of Billy on the Street, also starring Eichner. Klausner has written for television programs like Mulaney, Best Week Ever, The Big Gay Sketch Show, The Jack and Triumph Show, as well as pop culture websites like The Awl and Vulture. In 2012, Rolling Stone magazine featured her podcast How Was Your Week? in their list of "10 Best Comedy Podcasts of the Moment". In October 2011, The Hollywood Reporter reported that NBC had picked up a pilot based on Sue Margolis's novel, Apocalipstick, about a woman's father that dates her high-school nemesis; Klausner was set to write and executive produce the series. In recognition of her achievements, Klausner appears in Fast Company’s June 2012 '100 Most Creative People' issue.