Her acting debut came in 2001 in Robert Townsend's Carmen: A Hip Hopera. After a small role in the action comedy Showtime, she made her big breakthrough in Denzel Washington's directorial debut, Antwone Fisher. In 2003, she co-starred in the biography Baadasssss!, and in 2005, she appeared in several high-profile films, The Skeleton Key, London and Get Rich or Die Tryin'. She also played the role of Tunde Adebimpe's love interest in "Will Do" a 2011 TV on the Radio music video. From 2009-15, Bryant starred as Jasmine Trussell in Parenthood. BuddyTV ranked her #19 on its TV's 100 Sexiest Women of 2011 list.