In 1810, Goethe published his Theory of Colours, which he considered his most important work. In it, he contentiously characterized colour as arising from the dynamic interplay of light and darkness through the mediation of a turbid medium. In 1816, Schopenhauer went on to develop his own theory in On Vision and Colours based on the observations supplied in Goethe's book. After being translated into English by Charles Eastlake in 1840, his theory became widely adopted by the art world, most notably J. M. W. Turner. Goethe's work also inspired the Philosopher Ludwig Wittgenstein, to write his Remarks on Colour. Goethe was vehemently opposed to Newton's analytic treatment of colour, engaging instead in compiling a comprehensive rational description of a wide variety of colour phenomena. Although the accuracy of Goethe's observations does not admit a great deal of criticism, his aesthetic approach did not lend itself to the demands of analytic and mathematical analysis used ubiquitously in modern Science. Goethe was, however, the first to systematically study the physiological effects of colour, and his observations on the effect of opposed colours led him to a symmetric arrangement of his colour wheel, 'for the colours diametrically opposed to each other... are those which reciprocally evoke each other in the eye. (Goethe, Theory of Colours, 1810). In this, he anticipated Ewald Hering's opponent colour theory (1872).