He played Mark Antony in the HBO/BBC original television series, Rome. At the time there were rumours that at least one nude body in the show had been digitally enhanced. When his Wikipedia entry, which at that time referred to the rumours, was brought up in an interview with Alastair McKay, published in the January 2007 issue of Out magazine, Purefoy said, "I won't say whose it was, but there was a penis in the series that may have been slightly enhanced. But it wasn't mine. Mine's all mine."