House was born and grew up in rural Lily, Laurel County, Kentucky, but he also spent much of his childhood in nearby Leslie County, Kentucky, which he has cited as the basis for the fictional Crow County, which serves as the setting for his first three novels. He has degrees from Sue Bennett College (Associate's), Eastern Kentucky University (BA in English with emphasis on American literature), and from Spalding University (Master of Fine Arts in Creative Writing). In 2000, House was chosen, along with since-published authors Pamela Duncan, Jeanne Braselton, and Jack Riggs, as one of the ten emerging talents in the south by the Millennial Gathering of Writers at Vanderbilt University.