A 1953 newspaper article reported that Hedy Lamarr prompted Shane (described as Lamarr's "closest woman friend in recent years") to resume her career in film. Shane said of Lamarr, "She pushed me into a career again and got me out of my laziness." The article noted that Shane was "currently testing for the John Wayne picture, 'The High and the Mighty,' and the film version of 'Oklahoma.'" She returned to film and television work in 1955, most notably in the Clark Gable film The King and Four Queens. Her last film, 1959’s Tarzan's Greatest Adventure, in which she portrayed Angie, is considered her most memorable performance. She continued in television through 1964.