In 1980, Butler published the fourth book of the Patternist series, Wild Seed, whose narrative became the series' origin story. Set in Africa and America during the seventeenth century, Wild Seed traces the struggle between the four-thousand-year-old parapsychological vampire Doro and his "wild" child and bride, the three-hundred-year-old shapeshifter and healer Anyanwu. Doro, who has bred psionic children for centuries, deceives Anyanwu into becoming one of his breeders, but she eventually escapes and uses her gifts to create communities that rival Doro's. When Doro finally tracks her down, Anyanwu, tired by decades of escaping or fighting Doro, decides to commit suicide, forcing him to admit his need for her.