Naidu was born on 19 September 1980 in Vijayawada, Andhra Pradesh, India. Her father Ethiraj works for Air India and was a tennis coach and her mother Purnima, was a school Teacher. She has one younger sister, Sona. She told that she requested her mother to quit her job and accompany her to shooting locations, after her sister who used to travel with her got a job abroad. She grew up in Mumbai, Maharashtra, and considers herself "more of a Mumbaiite". She studied at Bhavan's College, Andheri, Mumbai, and graduated with a B.Com degree. She learned classical bharatanatyam dance for seven years. She stated that she also was coaching tennis in the US for four years.