From 1960 to 1961, she co-starred as Stacy in the syndicated western series Two Faces West, and Wagon Train. She later guest starred on The Asphalt Jungle, Bachelor Father, Maverick, 77 Sunset Strip, Alfred Hitchcock Presents, Sea Hunt, The Aquanauts, Bringing Up Buddy, and Slattery's People . She also made three appearances on Perry Mason, including the role of murder victim Sylvia Welles in the 1959 episode, "The Case of the Golden Fraud." In 1965, she portrayed Isobel Moon in the film Zebra in the Kitchen, starring Jay North. After appearing in The Christine Jorgensen Story in 1970, Meadows took a break from acting. She returned in 1987 with a guest role on Punky Brewster sitcom. During the first half of the 1990s, she guest starred on Lois and Clark: The New Adventures of Superman.