Slattery played Paul Moore, boyfriend of Katherine Watson (portrayed by Julia Roberts) in the film Mona Lisa Smile, and he portrayed Howie in David Lindsay-Abaire's play, Rabbit Hole. He had a small part as a Teacher in the film Sleepers. He also appeared as a government promoter in the Clint Eastwood feature Flags of our Fathers and as CIA official Henry Cravely in Charlie Wilson's War. He was cast as Bert Miller, Father of the leading female character, in Dirty Dancing: Havana Nights, and in The Adjustment Bureau played Richardson, a mid-level agent in the mysterious paranormal agency called the Bureau. Slattery narrates the audiobook version of Don DeLillo's 2007 novel Falling Man, Stephen King's 2008 psychological horror novel Duma Key, and Ernest Hemingway's 1929 novel A Farewell to Arms.