She appeared in episodes of, among other television shows, Dennis the Menace, I Love Lucy, Pete and Gladys, Hennesey, Death Valley Days, Get Smart, The Andy Griffith Show, Bewitched and The Golden Girls as well as in small film roles in The Manchurian Candidate, Hush, Hush, Sweet Charlotte and Room 222. She also appeared in a number of episodes of Dragnet, starring Jack Webb, during the 1950s. Helen Kleeb also appeared on many radio drama shows, some now playing on XM Satellite Radio.