He published 11 volumes of Fragmenta phytographica Australiae (1862–1881), two volumes of the Plants of Victoria (1860–1865), and other books on the Eucalyptus, Myoporaceae, Acacia, and Salsolaceae, all profusely illustrated. He also co-operated in the production of George Bentham's Flora Australiensis. He described many novel plant species sent by botanists from other parts of Australia, notably Maurice william Holtze from the Northern Territory, and encouraged settlers to send plants to him. Many women contributed to his collections, including Louisa Atkinson and Sarah Brooks He took a leading part in promoting Australian exploration, especially the Burke and Wills expedition, which was the first to cross the continent, and in the various attempts to unravel the mystery which attended the fate of his fellow countryman Ludwig Leichhardt (1813–1848).