Handler is also an author. His first book, Time On Fire: My Comedy of Terrors, tells the story of his unlikely recovery from acute myeloid leukemia in his mid-20s. His second, It's Only Temporary...The Good News and the Bad News of Being Alive, tells the story of his long journey toward gratitude in the years after his illness. The book was released in May 2008. Handler has written for several nationally distributed magazines, including ELLE, O, the Oprah Magazine, and Mirabella. Handler contributes regularly to The Huffington Post.