In 1768, Reed suffered the first of a series of strokes that severely impaired her speech and memory. For the remainder of her life, she suffered from poor health and depression. Despite his wife's condition, Franklin did not return to Philadelphia even though he had completed his diplomatic duties. In November 1769, Reed wrote Franklin saying that her stroke, declining health and depressed mental state were a result of her "dissatisfied distress" due to his prolonged absence. Franklin still did not return, but continued to write to Reed. Reed's final surviving letter to Franklin is dated October 29, 1773. Thereafter, she stopped corresponding with her husband. Franklin continued to write to Reed, inquiring as to why her letters had ceased, but still did not return home.