She fought Gina Carano on August 15, 2009, at Strikeforce: Carano vs. Cyborg for the Women's Featherweight Championship. Cyborg won via TKO at 4:59 of the 5:00 first round. The card was the first time that a major promotion had featured a main event between women. After the match, she hugged Carano, and stated in her interview that she had the utmost respect for Carano, and that it was an honor to fight her.