Therbusch's first recorded return to painting was in 1761 in the Stuttgart court of Duke Karl Eugen. She completed eighteen paintings in the shortest time for the castle gallery. In 1762 she became an honorary member of the Stuttgart Academy of the Arts and worked in Stuttgart and Mannheim. In 1765 she went to Paris. The French Royal Academy of Painting and Sculpture displayed her work first, proudly supporting a female Artist. Denis Diderot, the controversial and outspoken art critic and Philosopher, was sympathetic to her, even to the point of posing naked for her. Anna Dorothea finally joined the Academy in 1767, lived with Diderot and met famous artists, and even painted Philipp Hackert but she remained unsuccessful in Paris. That time is, however, seen as her most creative.