LaPlaca has guest-starred on series including ER, Cheers, Family Ties, Desperate Housewives, and Friends (as Rachel's boss, Joanna). She was a regular on Stat (1991), The Jackie Thomas Show (1992), Tom (1994), and the NBC sitcom The John Larroquette Show (from 1994 to 1996). LaPlaca has also guest-starred on animated series such as Johnny Bravo.