From 1962 to 1972, he served as the President of Smith, Miller and Patch, a pharmaceutical company. He sold Permalens, his family company, to Cooper Labs for $75 million in 1971, and founded Vision Cable in 1972. In 1982, he sold it to Samuel Irving Newhouse, Jr. and his brother for $220 million. Shortly after, he founded a cell phone company called Metro Mobile and later sold it to Bell Atlantic for $2.5 billion in 1991. He was then the CEO of Southern Union, a pipeline company, which was sold in 2012 to Energy Transfer Equity, LP for approximately $2.0 billion. He also owns 19 Spanish-speaking radio stations. He has been the President of Cellular Dynamics and the Managing General Partner of Activated Communications Limited Partnership since 1982. He has been a General Partner of Panhandle Eastern since 1990. He sits on the board of Directors of HI Europe Limited and on the advisory board of Hudson Clean Energy Partners.