Frédérique Bel made her acting debut in 2000 playing a small role in the comedy film Deuxième vie and later in the 2003 comedy film La Beuze. She then had famous supporting roles in comedy and romantic films. These include Tu vas rire, mais je te quitte in 2004, Imposture and The Russian Dolls in 2005. She portrayed Miss France in the 2006 science fiction comedy Un ticket pour l'espace and later featured in the comedy film Camping which had a box office of 5.5 million viewers. The same year, film Director Emmanuel Mouret gave her a role in his romantic comedy Change of Address, also featuring himself. She later featured in three other of his films, which are Shall We Kiss? in 2007, Fais-moi plaisir! in 2009, in which she appeared completely naked in one scene, and The Art of Love in 2011.