She played the free-spirited, adventurous intelligent, and intrusive Josie Trent on Strange Days at Blake Holsey High, also known as Black Hole High. At the 24th Annual Young Artist Awards (2003), Taylor-Isherwood was nominated for Supporting Young Actress in a TV series (comedy or drama), for the series. She was on a camping trip, when she found out she got the part as "Josie" on Strange Days.