In 2006, Clark set up a monthly comedy night called Clark's. He was the host and curated every show. It became a firm favourite among audiences and comics alike. A place where comedians would try out new ideas, it would often play host to some huge TV names, wanting to experiment. Its original home, between 2006–2009, was at the Lowdown at The Albany, a fringe venue below The Albany pub on Great Portland Street. In 2009, it moved to London's famous 100 Club on Oxford Street. It was revived for three nights in July 2013 at London's Soho Theatre. Among the many names that played there were Eddie Izzard, Noel Fielding, Jack Whitehall, Stephen Merchant, Cardinal Burns, Tim Key, Rich Fulcher, Oram & Meeten, Alice Lowe, Sarah Pascoe, Paul Foot, Tony Law, Arnab Chanda, and Sarah Kendall. Time Out said of the show, "One of the coolest nights in London is Clark's. Hosted by the utterly charming Dan Clark and is home to a lot of the new wave of young, offbeat, erudite comedians."