After numerous television guest appearances, Kasch got his big break when he was cast in a regular role on the sitcom Normal, Ohio, only for the series to be cancelled after a few episodes. Kasch portrayed a Texan high school student in the Australian teen comedy-drama series Out There. He played Zach Young, the son of deceased Mary Alice Young, on the ABC comedy-drama series Desperate Housewives. After a brief absence from the series, he returned in the third and seventh seasons as Gabrielle Solis' secret admirer. He is also the narrator for several audiobooks. He starred in the 2010 horror film Chain Letter.