Cullen's first television game show was the TV version of Winner Take All, which premiered on CBS in 1952. In 1953, Cullen had The Bill Cullen Show, a weekly morning variety program on CBS. He hosted Bank on the Stars in 1954. From 1954 to 1955, he hosted NBC's Place the Face, a program in which celebrities identified people from their past; he simultaneously hosted CBS's Name That Tune. From 1956 to 1966, he hosted the initial daytime and primetime versions of The Price Is Right, another Goodson-Todman production. He was also a panelist on I've Got a Secret from 1952 to 1967, and To Tell the Truth from 1969 to 1978, where he also guest hosted on occasion. After relocating to Southern California, Cullen guest hosted Password Plus for four weeks in April 1980 while original host Allen Ludden was being treated for stomach cancer.